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Effects of ZnT8 on epithelial-to-mesenchymal transition and tubulointerstitial fibrosis in diabetic kidney disease

Zinc transporter 8 (ZnT8) transports zinc ions for crystallization and storage of insulin in pancreatic beta-cells and ZnT8 dysfunction is involved in pathogenesis of diabetes. The current study aimed to investigate whether ZnT8 has effects in pathophysiology of diabetic kidney disease (DKD) by usin...

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Detalles Bibliográficos
Autores principales: Zhang, Xiuli, Guan, Tingwen, Yang, Boxuan, Gu, Harvest F., Chi, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367835/
https://www.ncbi.nlm.nih.gov/pubmed/32681069
http://dx.doi.org/10.1038/s41419-020-2731-6