3D genome organization contributes to genome instability at fragile sites

Common fragile sites (CFSs) are regions susceptible to replication stress and are hotspots for chromosomal instability in cancer. Several features were suggested to underlie CFS instability, however, these features are prevalent across the genome. Therefore, the molecular mechanisms underlying CFS i...

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Detalles Bibliográficos
Autores principales: Sarni, Dan, Sasaki, Takayo, Irony Tur-Sinai, Michal, Miron, Karin, Rivera-Mulia, Juan Carlos, Magnuson, Brian, Ljungman, Mats, Gilbert, David M., Kerem, Batsheva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367836/
https://www.ncbi.nlm.nih.gov/pubmed/32680994
http://dx.doi.org/10.1038/s41467-020-17448-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367836/
https://www.ncbi.nlm.nih.gov/pubmed/32680994
http://dx.doi.org/10.1038/s41467-020-17448-2

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