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Undetectable or subtherapeutic serum levels of antipsychotic drugs preceding switch to clozapine

Adequate antipsychotic treatment intensity is required for defining treatment-resistant schizophrenia (TRS) and justifying clozapine treatment. We investigated the occurrence of undetectable or subtherapeutic serum levels of oral antipsychotics preceding switch to clozapine as an endpoint of TRS. Fo...

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Detalles Bibliográficos
Autores principales: Kyllesø, Lennart, Smith, Robert Løvsletten, Karlstad, Øystein, Andreassen, Ole A., Molden, Espen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367852/
https://www.ncbi.nlm.nih.gov/pubmed/32681055
http://dx.doi.org/10.1038/s41537-020-0107-7