Reduced Brd1 expression leads to reversible depression-like behaviors and gene-expression changes in female mice

The schizophrenia-associated gene, BRD1, encodes an epigenetic regulator in which chromatin interactome is enriched with genes implicated in mental health. Alterations in histone modifications and epigenetic regulation contribute to brain transcriptomic changes in affective disorders and preclinical...

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Detalles Bibliográficos
Autores principales: Rajkumar, Anto P., Qvist, Per, Donskov, Julie G., Lazarus, Ross, Pallesen, Jonatan, Nava, Nicoletta, Winther, Gudrun, Liebenberg, Nico, Cour, Sanne H. la, Paternoster, Veerle, Fryland, Tue, Palmfeldt, Johan, Fejgin, Kim, Mørk, Arne, Nyegaard, Mette, Pakkenberg, Bente, Didriksen, Michael, Nyengaard, Jens R., Wegener, Gregers, Mors, Ole, Christensen, Jane H., Børglum, Anders D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367888/
https://www.ncbi.nlm.nih.gov/pubmed/32681022
http://dx.doi.org/10.1038/s41398-020-00914-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367888/
https://www.ncbi.nlm.nih.gov/pubmed/32681022
http://dx.doi.org/10.1038/s41398-020-00914-2

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