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Ex vivo/in vitro protective effect of myricetin bulk and nano-forms on PhIP-induced DNA damage in lymphocytes from healthy individuals and pre-cancerous MGUS patients

2-Amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) is a central dietary mutagen, produced when proteinaceous food is heated at very high temperatures potentially causing DNA strand breaks. This study investigates the protective potential of a well-researched flavonoid, myricetin in its bulk and...

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Detalles Bibliográficos
Autores principales: Akhtar, Shabana, Najafzadeh, Mojgan, Isreb, Mohammad, Newton, Lisa, Gopalan, Rajendran C., Anderson, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367907/
https://www.ncbi.nlm.nih.gov/pubmed/32342131
http://dx.doi.org/10.1007/s00204-020-02754-x