Enhancement of Oral Bioavailability of Ibandronate Through Gastroretentive Raft Forming Drug Delivery System: In Vitro and In Vivo Evaluation

BACKGROUND: Bisphosphonates have very low bioavailability and cause irritation of the esophagus and stomach. This study was planned to improve the oral bioavailability of ibandronate through the formation of a raft in the stomach. Bisphosphonate-induced irritation of the esophagus and stomach is pre...

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Detalles Bibliográficos
Autores principales: Hanif, Muhammad, Shah, Shahid, Rasul, Akhtar, Abbas, Ghulam, Zaman, Muhammad, Amjad, Muhammad Wahab, Abdul Ghafoor Raja, Maria, Khan, Hafeez Ullah, Ashfaq, Mehran, Iqbal, Omeira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367921/
https://www.ncbi.nlm.nih.gov/pubmed/32764922
http://dx.doi.org/10.2147/IJN.S255278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367921/
https://www.ncbi.nlm.nih.gov/pubmed/32764922
http://dx.doi.org/10.2147/IJN.S255278

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