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Enhancement of Oral Bioavailability of Ibandronate Through Gastroretentive Raft Forming Drug Delivery System: In Vitro and In Vivo Evaluation

BACKGROUND: Bisphosphonates have very low bioavailability and cause irritation of the esophagus and stomach. This study was planned to improve the oral bioavailability of ibandronate through the formation of a raft in the stomach. Bisphosphonate-induced irritation of the esophagus and stomach is pre...

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Detalles Bibliográficos
Autores principales:	Hanif, Muhammad, Shah, Shahid, Rasul, Akhtar, Abbas, Ghulam, Zaman, Muhammad, Amjad, Muhammad Wahab, Abdul Ghafoor Raja, Maria, Khan, Hafeez Ullah, Ashfaq, Mehran, Iqbal, Omeira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367921/ https://www.ncbi.nlm.nih.gov/pubmed/32764922 http://dx.doi.org/10.2147/IJN.S255278

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