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Crystal Structures, Stability, and Solubility Evaluation of a 2:1 Diosgenin–Piperazine Cocrystal

ABSTRACT: A cocrystal of diosgenin with piperazine in 2:1 stoichiometry was successfully synthesized. The solid form was prepared by liquid assisted grinding, slurry and crystallization methods. The cocrystal was characterized by powder X-ray diffraction, differential scanning calorimetry, thermogra...

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Detalles Bibliográficos
Autores principales: Gong, Ningbo, Yu, Hongmei, Wang, Ying, Xing, Cheng, Hu, Kun, Du, Guanhua, Lu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367958/
https://www.ncbi.nlm.nih.gov/pubmed/32632767
http://dx.doi.org/10.1007/s13659-020-00256-y