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Metronidazole conjugated magnetic nanoparticles loaded with amphotericin B exhibited potent effects against pathogenic Acanthamoeba castellanii belonging to the T4 genotype

Acanthamoeba castellanii can cause granulomatous amoebic encephalitis and Acanthamoeba keratitis. Currently, no single drug has been developed to effectively treat infections caused by Acanthamoeba. Recent studies have shown that drugs conjugated with nanoparticles exhibit potent in vitro antiamoebi...

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Detalles Bibliográficos
Autores principales: Abdelnasir, Sumayah, Anwar, Ayaz, Kawish, Muhammad, Anwar, Areeba, Shah, Muhammad Raza, Siddiqui, Ruqaiyyah, Khan, Naveed Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368000/
https://www.ncbi.nlm.nih.gov/pubmed/32681358
http://dx.doi.org/10.1186/s13568-020-01061-z