Detection of the thietane precursor in the UVA formation of the DNA 6-4 photoadduct

Notwithstanding the central biological role of the (6-4) photoadduct in the induction of skin cancer by sunlight, crucial mechanistic details about its formation have evaded characterization despite efforts spanning more than half a century. 4-Thiothymidine (4tT) has been widely used as an important...

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Detalles Bibliográficos
Autores principales: Ortiz-Rodríguez, Luis A., Reichardt, Christian, Hoehn, Sean J., Jockusch, Steffen, Crespo-Hernández, Carlos E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368040/
https://www.ncbi.nlm.nih.gov/pubmed/32680990
http://dx.doi.org/10.1038/s41467-020-17333-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368040/
https://www.ncbi.nlm.nih.gov/pubmed/32680990
http://dx.doi.org/10.1038/s41467-020-17333-y

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