Coordinate β-adrenergic inhibition of mitochondrial activity and angiogenesis arrest tumor growth

Mitochondrial metabolism has emerged as a promising target against the mechanisms of tumor growth. Herein, we have screened an FDA-approved library to identify drugs that inhibit mitochondrial respiration. The β1-blocker nebivolol specifically hinders oxidative phosphorylation in cancer cells by con...

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Detalles Bibliográficos
Autores principales: Nuevo-Tapioles, Cristina, Santacatterina, Fulvio, Stamatakis, Konstantinos, Núñez de Arenas, Cristina, Gómez de Cedrón, Marta, Formentini, Laura, Cuezva, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368041/
https://www.ncbi.nlm.nih.gov/pubmed/32681016
http://dx.doi.org/10.1038/s41467-020-17384-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368041/
https://www.ncbi.nlm.nih.gov/pubmed/32681016
http://dx.doi.org/10.1038/s41467-020-17384-1

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