Cargando…
Coordinate β-adrenergic inhibition of mitochondrial activity and angiogenesis arrest tumor growth
Mitochondrial metabolism has emerged as a promising target against the mechanisms of tumor growth. Herein, we have screened an FDA-approved library to identify drugs that inhibit mitochondrial respiration. The β1-blocker nebivolol specifically hinders oxidative phosphorylation in cancer cells by con...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368041/ https://www.ncbi.nlm.nih.gov/pubmed/32681016 http://dx.doi.org/10.1038/s41467-020-17384-1 |