A molecular docking study revealed that synthetic peptides induced conformational changes in the structure of SARS-CoV-2 spike glycoprotein, disrupting the interaction with human ACE2 receptor

The global outbreak of COVID-19 (Coronavirus Disease 2019) caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome caused by Coronavirus 2) began in December 2019. Its closest relative, SARS-CoV-1, has a slightly mutated Spike (S) protein, which interacts with ACE2 receptor in human cells to start t...

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Detalles Bibliográficos
Autores principales: Souza, Pedro F.N., Lopes, Francisco E.S., Amaral, Jackson L., Freitas, Cleverson D.T., Oliveira, Jose T.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368152/
https://www.ncbi.nlm.nih.gov/pubmed/32693122
http://dx.doi.org/10.1016/j.ijbiomac.2020.07.174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368152/
https://www.ncbi.nlm.nih.gov/pubmed/32693122
http://dx.doi.org/10.1016/j.ijbiomac.2020.07.174

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