Cofactor-enabled functional expression of fruit fly, honeybee, and bumblebee nicotinic receptors reveals picomolar neonicotinoid actions

The difficulty of achieving robust functional expression of insect nicotinic acetylcholine receptors (nAChRs) has hampered our understanding of these important molecular targets of globally deployed neonicotinoid insecticides at a time when concerns have grown regarding the toxicity of this chemotyp...

Descripción completa

Detalles Bibliográficos
Autores principales: Ihara, Makoto, Furutani, Shogo, Shigetou, Sho, Shimada, Shota, Niki, Kunihiro, Komori, Yuma, Kamiya, Masaki, Koizumi, Wataru, Magara, Leo, Hikida, Mai, Noguchi, Akira, Okuhara, Daiki, Yoshinari, Yuto, Kondo, Shu, Tanimoto, Hiromu, Niwa, Ryusuke, Sattelle, David B., Matsuda, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368294/
https://www.ncbi.nlm.nih.gov/pubmed/32611810
http://dx.doi.org/10.1073/pnas.2003667117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368294/
https://www.ncbi.nlm.nih.gov/pubmed/32611810
http://dx.doi.org/10.1073/pnas.2003667117

Ejemplares similares