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Cofactor-enabled functional expression of fruit fly, honeybee, and bumblebee nicotinic receptors reveals picomolar neonicotinoid actions
The difficulty of achieving robust functional expression of insect nicotinic acetylcholine receptors (nAChRs) has hampered our understanding of these important molecular targets of globally deployed neonicotinoid insecticides at a time when concerns have grown regarding the toxicity of this chemotyp...
Autores principales: | Ihara, Makoto, Furutani, Shogo, Shigetou, Sho, Shimada, Shota, Niki, Kunihiro, Komori, Yuma, Kamiya, Masaki, Koizumi, Wataru, Magara, Leo, Hikida, Mai, Noguchi, Akira, Okuhara, Daiki, Yoshinari, Yuto, Kondo, Shu, Tanimoto, Hiromu, Niwa, Ryusuke, Sattelle, David B., Matsuda, Kazuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368294/ https://www.ncbi.nlm.nih.gov/pubmed/32611810 http://dx.doi.org/10.1073/pnas.2003667117 |
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