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A lipocalin mediates unidirectional heme biomineralization in malaria parasites

During blood-stage development, malaria parasites are challenged with the detoxification of enormous amounts of heme released during the proteolytic catabolism of erythrocytic hemoglobin. They tackle this problem by sequestering heme into bioinert crystals known as hemozoin. The mechanisms underlyin...

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Detalles Bibliográficos
Autores principales: Matz, Joachim M., Drepper, Benjamin, Blum, Thorsten B., van Genderen, Eric, Burrell, Alana, Martin, Peer, Stach, Thomas, Collinson, Lucy M., Abrahams, Jan Pieter, Matuschewski, Kai, Blackman, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368307/
https://www.ncbi.nlm.nih.gov/pubmed/32601225
http://dx.doi.org/10.1073/pnas.2001153117