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FTY720 Attenuates Neuropathic Pain after Spinal Cord Injury by Decreasing Systemic and Local Inflammation in a Rat Spinal Cord Compression Model

Neuropathic pain severely impairs rehabilitation and quality of life after spinal cord injury (SCI). The sphingosine-1-phosphate receptor agonist, FTY720, plays an important protective role in neuronal injury. This study aims to examine the effects of FTY720 in a rat acute SCI model, focusing on neu...

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Detalles Bibliográficos
Autores principales: Yamazaki, Kazuyoshi, Kawabori, Masahito, Seki, Toshitaka, Takamiya, Soichiro, Tateno, Takahiro, Konno, Kotaro, Watanabe, Masahiko, Houkin, Kiyohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368387/
https://www.ncbi.nlm.nih.gov/pubmed/32216535
http://dx.doi.org/10.1089/neu.2019.6905