Cervicovaginal cellular angiofibroma
Cellular angiofibroma is a rare type of benign mesenchymal tumour that arises mostly in middle-aged women. It needs to be distinguished from other neoplasms and has a predilection for the vulvovaginal region. To our knowledge, this is the first case of a cervical cellular angiofibroma. A 34-year-old...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368490/ https://www.ncbi.nlm.nih.gov/pubmed/32675122 http://dx.doi.org/10.1136/bcr-2020-235241 |
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author | Van Mulders, Sarah Faes, Ellen Broeckx, Glenn Jacquemyn, Yves |
author_facet | Van Mulders, Sarah Faes, Ellen Broeckx, Glenn Jacquemyn, Yves |
author_sort | Van Mulders, Sarah |
collection | PubMed |
description | Cellular angiofibroma is a rare type of benign mesenchymal tumour that arises mostly in middle-aged women. It needs to be distinguished from other neoplasms and has a predilection for the vulvovaginal region. To our knowledge, this is the first case of a cervical cellular angiofibroma. A 34-year-old nulligravid woman was referred with a large mass bulging in the fornix posterior. Ultrasound scanning and MRI showed a large solid mass projecting in the pouch of Douglas. Laparoscopic surgical excision was performed. Histopathological examination showed a well-demarcated, unencapsulated tumour, consisting of short fascicles of spindle cells in-between thick-walled medium-sized vessels. On immunohistochemistry, there was strong reactivity with antibodies against CD34 and oestrogen receptor. Angiofibromas are benign mesenchymal tumours mostly occurring in middle-aged women. They can cause abnormal swelling and uterine bleeding and need to be distinguished from other (malignant) neoplasms. |
format | Online Article Text |
id | pubmed-7368490 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-73684902020-07-22 Cervicovaginal cellular angiofibroma Van Mulders, Sarah Faes, Ellen Broeckx, Glenn Jacquemyn, Yves BMJ Case Rep Unusual Presentation of More Common Disease/Injury Cellular angiofibroma is a rare type of benign mesenchymal tumour that arises mostly in middle-aged women. It needs to be distinguished from other neoplasms and has a predilection for the vulvovaginal region. To our knowledge, this is the first case of a cervical cellular angiofibroma. A 34-year-old nulligravid woman was referred with a large mass bulging in the fornix posterior. Ultrasound scanning and MRI showed a large solid mass projecting in the pouch of Douglas. Laparoscopic surgical excision was performed. Histopathological examination showed a well-demarcated, unencapsulated tumour, consisting of short fascicles of spindle cells in-between thick-walled medium-sized vessels. On immunohistochemistry, there was strong reactivity with antibodies against CD34 and oestrogen receptor. Angiofibromas are benign mesenchymal tumours mostly occurring in middle-aged women. They can cause abnormal swelling and uterine bleeding and need to be distinguished from other (malignant) neoplasms. BMJ Publishing Group 2020-07-16 /pmc/articles/PMC7368490/ /pubmed/32675122 http://dx.doi.org/10.1136/bcr-2020-235241 Text en © BMJ Publishing Group Limited 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Unusual Presentation of More Common Disease/Injury Van Mulders, Sarah Faes, Ellen Broeckx, Glenn Jacquemyn, Yves Cervicovaginal cellular angiofibroma |
title | Cervicovaginal cellular angiofibroma |
title_full | Cervicovaginal cellular angiofibroma |
title_fullStr | Cervicovaginal cellular angiofibroma |
title_full_unstemmed | Cervicovaginal cellular angiofibroma |
title_short | Cervicovaginal cellular angiofibroma |
title_sort | cervicovaginal cellular angiofibroma |
topic | Unusual Presentation of More Common Disease/Injury |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368490/ https://www.ncbi.nlm.nih.gov/pubmed/32675122 http://dx.doi.org/10.1136/bcr-2020-235241 |
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