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Hematopoietic lineage-converted T cells carrying tumor-associated antigen-recognizing TCRs effectively kill tumor cells

Tumor-associated antigen (TAA) T-cell receptor (TCR) gene-engineered T cells exhibit great potential in antitumor immunotherapy. Considering the high costs and low availability of patient-derived peripheral blood T cells, substantial efforts have been made to explore alternatives to natural T cells....

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Detalles Bibliográficos
Autores principales: Hu, Fangxiao, Huang, Dehao, Luo, Yuxuan, Zhou, Peiqing, Lv, Cui, Wang, Kaitao, Weng, Qitong, Liu, Xiaofei, Guan, Yuxian, Geng, Yang, Du, Juan, Chen, Jiekai, Wang, Jinyong, Wu, Hongling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368548/
https://www.ncbi.nlm.nih.gov/pubmed/32669292
http://dx.doi.org/10.1136/jitc-2019-000498