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Promising Swellable Floating Bupropion Tablets: Formulation, in vitro/in vivo Evaluation and Comparative Pharmacokinetic Study in Human Volunteers

PURPOSE: Bupropion is an antidepressant drug that facilitates weight loss. It is a highly water-soluble drug that needs multiple dosing, so it is considered a potential candidate for oral controlled-release dosage form. The aim of this research was to formulate and evaluate satiety-inducing swellabl...

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Detalles Bibliográficos
Autores principales: Teaima, Mahmoud, Abdel Hamid, Magdi M., Shoman, Nabil A., Jasti, Bhaskara R., El-Nabarawi, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368561/
https://www.ncbi.nlm.nih.gov/pubmed/32764875
http://dx.doi.org/10.2147/DDDT.S258571