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Plasma Lipidome, PNPLA3 polymorphism and hepatic steatosis in hereditary hemochromatosis

BACKGROUND: Hereditary hemochromatosis (HH) is an autosomal recessive genetic disorder with increased intestinal iron absorption and therefore iron Overload. iron overload leads to increased levels of toxic non-transferrin bound iron which results in oxidative stress and lipid peroxidation. The impa...

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Detalles Bibliográficos
Autores principales: Seeßle, Jessica, Gan-Schreier, Hongying, Kirchner, Marietta, Stremmel, Wolfgang, Chamulitrat, Walee, Merle, Uta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368730/
https://www.ncbi.nlm.nih.gov/pubmed/32680469
http://dx.doi.org/10.1186/s12876-020-01282-3