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The SPLUNC1-βENaC complex prevents Burkholderia cenocepacia invasion in normal airway epithelia

Cystic fibrosis (CF) patients are extremely vulnerable to Burkholderia cepacia complex (Bcc) infections. However, the underlying etiology is poorly understood. We tested the hypothesis that short palate lung and nasal epithelial clone 1 (SPLUNC1)–epithelial sodium channel (ENaC) interactions at the...

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Detalles Bibliográficos
Autores principales: Ahmad, Saira, Kim, Christine Seul Ki, Tarran, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368771/
https://www.ncbi.nlm.nih.gov/pubmed/32680508
http://dx.doi.org/10.1186/s12931-020-01454-5