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Metformin Protects ARPE-19 Cells from Glyoxal-Induced Oxidative Stress

The protective effects and mechanisms of metformin against oxidative stress were evaluated both in vivo and in vitro. ARPE-19 cells comprised the normal group, the glyoxal-treated group (0.5 mM glyoxal), and the glyoxal+metformin group (0.5 mM glyoxal and 0.1 mM metformin). In the in vitro model, di...

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Detalles Bibliográficos
Autores principales: Qu, Sichang, Zhang, Chaoyang, Liu, Dandan, Wu, Jing, Tian, Haibin, Lu, Lixia, Xu, Guo-Tong, Liu, Fang, Zhang, Jingfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368933/
https://www.ncbi.nlm.nih.gov/pubmed/32695253
http://dx.doi.org/10.1155/2020/1740943