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Metformin Protects ARPE-19 Cells from Glyoxal-Induced Oxidative Stress
The protective effects and mechanisms of metformin against oxidative stress were evaluated both in vivo and in vitro. ARPE-19 cells comprised the normal group, the glyoxal-treated group (0.5 mM glyoxal), and the glyoxal+metformin group (0.5 mM glyoxal and 0.1 mM metformin). In the in vitro model, di...
Autores principales: | Qu, Sichang, Zhang, Chaoyang, Liu, Dandan, Wu, Jing, Tian, Haibin, Lu, Lixia, Xu, Guo-Tong, Liu, Fang, Zhang, Jingfa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368933/ https://www.ncbi.nlm.nih.gov/pubmed/32695253 http://dx.doi.org/10.1155/2020/1740943 |
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