Alzheimer’s Disease-Like Neurodegeneration in Porphyromonas gingivalis Infected Neurons with Persistent Expression of Active Gingipains

BACKGROUND: Porphyromonas gingivalis (P. gingivalis) and its gingipain virulence factors have been identified as pathogenic effectors in Alzheimer’s disease (AD). In a recent study we demonstrated the presence of gingipains in over 90% of postmortem AD brains, with gingipains localizing to the cytop...

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Detalles Bibliográficos
Autores principales: Haditsch, Ursula, Roth, Theresa, Rodriguez, Leo, Hancock, Sandy, Cecere, Thomas, Nguyen, Mai, Arastu-Kapur, Shirin, Broce, Sean, Raha, Debasish, Lynch, Casey C., Holsinger, Leslie J., Dominy, Stephen S., Ermini, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369049/
https://www.ncbi.nlm.nih.gov/pubmed/32390638
http://dx.doi.org/10.3233/JAD-200393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369049/
https://www.ncbi.nlm.nih.gov/pubmed/32390638
http://dx.doi.org/10.3233/JAD-200393

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