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Alzheimer’s Disease-Like Neurodegeneration in Porphyromonas gingivalis Infected Neurons with Persistent Expression of Active Gingipains

BACKGROUND: Porphyromonas gingivalis (P. gingivalis) and its gingipain virulence factors have been identified as pathogenic effectors in Alzheimer’s disease (AD). In a recent study we demonstrated the presence of gingipains in over 90% of postmortem AD brains, with gingipains localizing to the cytop...

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Detalles Bibliográficos
Autores principales:	Haditsch, Ursula, Roth, Theresa, Rodriguez, Leo, Hancock, Sandy, Cecere, Thomas, Nguyen, Mai, Arastu-Kapur, Shirin, Broce, Sean, Raha, Debasish, Lynch, Casey C., Holsinger, Leslie J., Dominy, Stephen S., Ermini, Florian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369049/ https://www.ncbi.nlm.nih.gov/pubmed/32390638 http://dx.doi.org/10.3233/JAD-200393

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