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Serum Hepcidin Levels in Cognitively Normal Older Adults with High Neocortical Amyloid-β Load

BACKGROUND/OBJECTIVE: Hepcidin, an iron-regulating hormone, suppresses the release of iron by binding to the iron exporter protein, ferroportin, resulting in intracellular iron accumulation. Given that iron dyshomeostasis has been observed in Alzheimer’s disease (AD) together with elevated serum hep...

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Detalles Bibliográficos
Autores principales: Chatterjee, Pratishtha, Mohammadi, Maryam, Goozee, Kathryn, Shah, Tejal M., Sohrabi, Hamid R., Dias, Cintia B., Shen, Kaikai, Asih, Prita R., Dave, Preeti, Pedrini, Steve, Ashton, Nicholas J., Hye, Abdul, Taddei, Kevin, Lovejoy, David B., Zetterberg, Henrik, Blennow, Kaj, Martins, Ralph N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369053/
https://www.ncbi.nlm.nih.gov/pubmed/32538848
http://dx.doi.org/10.3233/JAD-200162