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APOE4 Status is Related to Differences in Memory-Related Brain Function in Asymptomatic Older Adults with Family History of Alzheimer’s Disease: Baseline Analysis of the PREVENT-AD Task Functional MRI Dataset

BACKGROUND: Episodic memory decline is one of the earliest symptoms of late-onset Alzheimer’s disease (AD). Older adults with the apolipoprotein E ɛ4 (+APOE4) genetic risk factor for AD may exhibit altered patterns of memory-related brain activity years prior to initial symptom onset. OBJECTIVE: Her...

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Detalles Bibliográficos
Autores principales: Rabipour, Sheida, Rajagopal, Sricharana, Yu, Elsa, Pasvanis, Stamatoula, Lafaille-Magnan, Marie-Elyse, Breitner, John, Rajah, M. Natasha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369116/
https://www.ncbi.nlm.nih.gov/pubmed/32474466
http://dx.doi.org/10.3233/JAD-191292