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Early Cognitive Training Rescues Remote Spatial Memory but Reduces Cognitive Flexibility in Alzheimer’s Disease Mice

BACKGROUND: Spatial memory dysfunction has been demonstrated in mouse models of Alzheimer’s disease (AD) which is consistent with the clinical finding that the early signature of AD includes difficulties in the formation and/or storage of a memory. A stored memory—a long term memory—can be modulated...

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Detalles Bibliográficos
Autores principales: Rai, Surya Prakash, Krohn, Markus, Pahnke, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369118/
https://www.ncbi.nlm.nih.gov/pubmed/32417783
http://dx.doi.org/10.3233/JAD-200161