Triterpenoid CDDO-Me induces ROS generation and up-regulates cellular levels of antioxidative enzymes without induction of DSBs in human peripheral blood mononuclear cells

Ionizing radiation produces reactive oxygen species (ROS) leading to cellular DNA damage. Therefore, patients undergoing radiation therapy or first responders in radiological accident scenarios could both benefit from the identification of specifically acting pharmacological radiomitigators. The syn...

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Detalles Bibliográficos
Autores principales: Beinke, Christina, Scherthan, Harry, Port, Matthias, Popp, Tanja, Hermann, Cornelius, Eder, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369132/
https://www.ncbi.nlm.nih.gov/pubmed/32409897
http://dx.doi.org/10.1007/s00411-020-00847-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369132/
https://www.ncbi.nlm.nih.gov/pubmed/32409897
http://dx.doi.org/10.1007/s00411-020-00847-w

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