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Immune checkpoint inhibitors in malignant lymphoma: Advances and perspectives

Classical Hodgkin lymphoma (cHL) has been identified with universal genetic alterations of chromosome 9p24.1, which contains PD-L1/PD-L2 genes. The amplification of 9p24.1 is associated with the increased expression of PD-L1 and PD-L2 on RS cells, which promotes their immune evasion, and subsequentl...

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Detalles Bibliográficos
Autores principales: Lin, Ningjing, Song, Yuqin, Zhu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369179/
https://www.ncbi.nlm.nih.gov/pubmed/32694896
http://dx.doi.org/10.21147/j.issn.1000-9604.2020.03.03