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Are Wnt/β-Catenin and PI3K/AKT/mTORC1 Distinct Pathways in Colorectal Cancer?

Wnt/β-catenin and phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin complex 1 (PI3K/AKT/mTORC1) pathways both are critically involved in colorectal cancer (CRC) development, although they are implicated in the modulation of distinct oncogenic mechanisms. In homeostatic and...

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Detalles Bibliográficos
Autores principales: Prossomariti, Anna, Piazzi, Giulia, Alquati, Chiara, Ricciardiello, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369353/
https://www.ncbi.nlm.nih.gov/pubmed/32334125
http://dx.doi.org/10.1016/j.jcmgh.2020.04.007