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Synthetic mRNA Encoding VEGF-A in Patients Undergoing Coronary Artery Bypass Grafting: Design of a Phase 2a Clinical Trial

Therapeutic angiogenesis may improve outcomes in patients with coronary artery disease undergoing surgical revascularization. Angiogenic factors may promote blood vessel growth and regenerate regions of ischemic but viable myocardium. Previous clinical trials of vascular endothelial growth factor A...

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Detalles Bibliográficos
Autores principales: Anttila, Vesa, Saraste, Antti, Knuuti, Juhani, Jaakkola, Pekka, Hedman, Marja, Svedlund, Sara, Lagerström-Fermér, Maria, Kjaer, Magnus, Jeppsson, Anders, Gan, Li-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369517/
https://www.ncbi.nlm.nih.gov/pubmed/32728595
http://dx.doi.org/10.1016/j.omtm.2020.05.030