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DDI2 Is a Ubiquitin-Directed Endoprotease Responsible for Cleavage of Transcription Factor NRF1

The Ddi1/DDI2 proteins are ubiquitin shuttling factors, implicated in a variety of cellular functions. In addition to ubiquitin-binding and ubiquitin-like domains, they contain a conserved region with similarity to retroviral proteases, but whether and how DDI2 functions as a protease has remained u...

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Detalles Bibliográficos
Autores principales: Dirac-Svejstrup, A. Barbara, Walker, Jane, Faull, Peter, Encheva, Vesela, Akimov, Vyacheslav, Puglia, Michele, Perkins, David, Kümper, Sandra, Hunjan, Suchete S., Blagoev, Blagoy, Snijders, Ambrosius P., Powell, David J., Svejstrup, Jesper Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369636/
https://www.ncbi.nlm.nih.gov/pubmed/32521225
http://dx.doi.org/10.1016/j.molcel.2020.05.035