An Inhibitor of DRP1 (Mdivi-1) Alleviates LPS-Induced Septic AKI by Inhibiting NLRP3 Inflammasome Activation

Mitochondria play an essential role in energy metabolism. Oxygen deprivation can poison cells and generate a chain reaction due to the free radical release. In patients with sepsis, the kidneys tend to be the organ primarily affected and the proximal renal tubules are highly susceptible to energy me...

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Detalles Bibliográficos
Autores principales: Liu, Ruijin, Wang, Si-cong, Li, Ming, Ma, Xiao-hui, Jia, Xiao-nan, Bu, Yue, Sun, Lei, Yu, Kai-jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369665/
https://www.ncbi.nlm.nih.gov/pubmed/32733934
http://dx.doi.org/10.1155/2020/2398420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369665/
https://www.ncbi.nlm.nih.gov/pubmed/32733934
http://dx.doi.org/10.1155/2020/2398420

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