The Specific IKKε/TBK1 Inhibitor Amlexanox Suppresses Human Melanoma by the Inhibition of Autophagy, NF-κB and MAP Kinase Pathways

Inhibitor-kappaB kinase epsilon (IKKε) and TANK-binding kinase 1 (TBK1) are non-canonical IκB kinases, both described as contributors to tumor growth and metastasis in different cancer types. Several hints indicate that they are also involved in the pathogenesis of melanoma; however, the impact of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Möller, Moritz, Wasel, Julia, Schmetzer, Julia, Weiß, Ulrike, Meissner, Markus, Schiffmann, Susanne, Weigert, Andreas, Möser, Christine V., Niederberger, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369692/
https://www.ncbi.nlm.nih.gov/pubmed/32630674
http://dx.doi.org/10.3390/ijms21134721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369692/
https://www.ncbi.nlm.nih.gov/pubmed/32630674
http://dx.doi.org/10.3390/ijms21134721

Ejemplares similares