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Nonsense Suppression Therapy: New Hypothesis for the Treatment of Inherited Bone Marrow Failure Syndromes

Inherited bone marrow failure syndromes (IBMFS) are a group of cancer-prone genetic diseases characterized by hypocellular bone marrow with impairment in one or more hematopoietic lineages. The pathogenesis of IBMFS involves mutations in several genes which encode for proteins involved in DNA repair...

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Detalles Bibliográficos
Autores principales: Bezzerri, Valentino, Api, Martina, Allegri, Marisole, Fabrizzi, Benedetta, Corey, Seth J., Cipolli, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369780/
https://www.ncbi.nlm.nih.gov/pubmed/32630050
http://dx.doi.org/10.3390/ijms21134672