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Oxidation of Erythrocytes Enhance the Production of Reactive Species in the Presence of Artemisinins

In red blood cells, hemoglobin iron represents the most plausible candidate to catalyze artemisinin activation but the limited reactivity of iron bound to hemoglobin does not play in favor for its direct involvement. Denatured hemoglobin appears a more likely candidate for artemisinin redox activati...

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Detalles Bibliográficos
Autores principales: Tsamesidis, Ioannis, Pério, Pierre, Pantaleo, Antonella, Reybier, Karine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369783/
https://www.ncbi.nlm.nih.gov/pubmed/32646002
http://dx.doi.org/10.3390/ijms21134799