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The Novel gem-Dihydroperoxide 12AC3O Suppresses High Phosphate-Induced Calcification via Antioxidant Effects in p53LMAco1 Smooth Muscle Cells

The excessive intake of phosphate (Pi), or chronic kidney disease (CKD), can cause hyperphosphatemia and eventually lead to ectopic calcification, resulting in cerebrovascular diseases. It has been reported that reactive oxygen species (ROS), induced by high concentrations of Pi loading, play a key...

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Detalles Bibliográficos
Autores principales: Takase, Naoko, Inden, Masatoshi, Hirai, Shunsuke, Yamada, Yumeka, Kurita, Hisaka, Takeda, Mitsumi, Yamaguchi, Eiji, Itoh, Akichika, Hozumi, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369805/
https://www.ncbi.nlm.nih.gov/pubmed/32610684
http://dx.doi.org/10.3390/ijms21134628