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The Novel gem-Dihydroperoxide 12AC3O Suppresses High Phosphate-Induced Calcification via Antioxidant Effects in p53LMAco1 Smooth Muscle Cells
The excessive intake of phosphate (Pi), or chronic kidney disease (CKD), can cause hyperphosphatemia and eventually lead to ectopic calcification, resulting in cerebrovascular diseases. It has been reported that reactive oxygen species (ROS), induced by high concentrations of Pi loading, play a key...
Autores principales: | Takase, Naoko, Inden, Masatoshi, Hirai, Shunsuke, Yamada, Yumeka, Kurita, Hisaka, Takeda, Mitsumi, Yamaguchi, Eiji, Itoh, Akichika, Hozumi, Isao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369805/ https://www.ncbi.nlm.nih.gov/pubmed/32610684 http://dx.doi.org/10.3390/ijms21134628 |
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