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Anti-Inflammatory and General Glucocorticoid Physiology in Skeletal Muscles Affected by Duchenne Muscular Dystrophy: Exploration of Steroid-Sparing Agents

In Duchenne muscular dystrophy (DMD), the activation of proinflammatory and metabolic cellular pathways in skeletal muscle cells is an inherent characteristic. Synthetic glucocorticoid intake counteracts the majority of these mechanisms. However, glucocorticoids induce burdensome secondary effects,...

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Detalles Bibliográficos
Autores principales: Herbelet, Sandrine, Rodenbach, Arthur, De Paepe, Boel, De Bleecker, Jan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369834/
https://www.ncbi.nlm.nih.gov/pubmed/32605223
http://dx.doi.org/10.3390/ijms21134596