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Inhibition of Eukaryotic Translation Initiation Factor 5A (eIF5A) Hypusination Suppress p53 Translation and Alters the Association of eIF5A to the Ribosomes

The eukaryotic translation initiation factor 5A (eIF5A) is an essential protein for the viability of the cells whose proposed function is to prevent the stalling of the ribosomes during translation elongation. eIF5A activity requires a unique and functionally essential post-translational modificatio...

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Detalles Bibliográficos
Autores principales: Martella, Marianna, Catalanotto, Caterina, Talora, Claudio, La Teana, Anna, Londei, Paola, Benelli, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369855/
https://www.ncbi.nlm.nih.gov/pubmed/32605139
http://dx.doi.org/10.3390/ijms21134583