The HSP90 Inhibitor, AUY-922, Ameliorates the Development of Nitrogen Mustard-Induced Pulmonary Fibrosis and Lung Dysfunction in Mice

Increased levels of heat shock protein 90 (HSP90) have been recently implicated in the pathogenesis of pulmonary fibrosis and the use of HSP90 inhibitors constitutes a potential therapeutic approach. Similarly, acute exposure to nitrogen mustard (NM) is related to the development of chronic lung inj...

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Detalles Bibliográficos
Autores principales: Solopov, Pavel, Colunga Biancatelli, Ruben M. L., Marinova, Margarita, Dimitropoulou, Christiana, Catravas, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369861/
https://www.ncbi.nlm.nih.gov/pubmed/32635192
http://dx.doi.org/10.3390/ijms21134740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369861/
https://www.ncbi.nlm.nih.gov/pubmed/32635192
http://dx.doi.org/10.3390/ijms21134740

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