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The HSP90 Inhibitor, AUY-922, Ameliorates the Development of Nitrogen Mustard-Induced Pulmonary Fibrosis and Lung Dysfunction in Mice
Increased levels of heat shock protein 90 (HSP90) have been recently implicated in the pathogenesis of pulmonary fibrosis and the use of HSP90 inhibitors constitutes a potential therapeutic approach. Similarly, acute exposure to nitrogen mustard (NM) is related to the development of chronic lung inj...
Autores principales: | Solopov, Pavel, Colunga Biancatelli, Ruben M. L., Marinova, Margarita, Dimitropoulou, Christiana, Catravas, John D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369861/ https://www.ncbi.nlm.nih.gov/pubmed/32635192 http://dx.doi.org/10.3390/ijms21134740 |
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