Evaluating the Performance of a Non-Bonded Cu(2+) Model Including Jahn−Teller Effect into the Binding of Tyrosinase Inhibitors

Tyrosinase (TYR) is a metalloenzyme classified as a type-3 copper protein, which is involved in the synthesis of melanin through a catalytic process beginning with the conversion of the amino acid l-Tyrosine (l-Tyr) to l-3,4-dihydroxyphenylalanine (l-DOPA). It plays an important role in the mechanis...

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Detalles Bibliográficos
Autores principales: Martins, Lucas Sousa, Lameira, Jerônimo, Kruger, Hendrik G., Alves, Cláudio Nahum, Silva, José Rogério A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369908/
https://www.ncbi.nlm.nih.gov/pubmed/32640730
http://dx.doi.org/10.3390/ijms21134783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369908/
https://www.ncbi.nlm.nih.gov/pubmed/32640730
http://dx.doi.org/10.3390/ijms21134783

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