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Evaluating the Performance of a Non-Bonded Cu(2+) Model Including Jahn−Teller Effect into the Binding of Tyrosinase Inhibitors
Tyrosinase (TYR) is a metalloenzyme classified as a type-3 copper protein, which is involved in the synthesis of melanin through a catalytic process beginning with the conversion of the amino acid l-Tyrosine (l-Tyr) to l-3,4-dihydroxyphenylalanine (l-DOPA). It plays an important role in the mechanis...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369908/ https://www.ncbi.nlm.nih.gov/pubmed/32640730 http://dx.doi.org/10.3390/ijms21134783 |