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NRF2 Knockdown Resensitizes 5-Fluorouracil-Resistant Pancreatic Cancer Cells by Suppressing HO-1 and ABCG2 Expression

Chemoresistance is a leading cause of morbidity and mortality in patients with pancreatic cancer and remains an obstacle to successful treatment. The antioxidant transcription factor nuclear factor (erythroid-derived 2)-related factor 2 (NRF2), which plays important roles in tumor angiogenesis and i...

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Detalles Bibliográficos
Autores principales: Kim, Eui Joo, Kim, Yoon Jae, Lee, Hye In, Jeong, Seok-Hoo, Nam, Hyo Jung, Cho, Jae Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369955/
https://www.ncbi.nlm.nih.gov/pubmed/32629871
http://dx.doi.org/10.3390/ijms21134646