Differences in the Role of HDACs 4 and 5 in the Modulation of Processes Regulating MAFbx and MuRF1 Expression during Muscle Unloading

Unloading leads to skeletal muscle atrophy via the upregulation of MuRF-1 and MAFbx E3-ligases expression. Reportedly, histone deacetylases (HDACs) 4 and 5 may regulate the expression of MuRF1 and MAFbx. To examine the HDAC-dependent mechanisms involved in the control of E3-ubiquitin ligases express...

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Detalles Bibliográficos
Autores principales: Mochalova, Ekaterina P., Belova, Svetlana P., Kostrominova, Tatiana Y., Shenkman, Boris S., Nemirovskaya, Tatiana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370043/
https://www.ncbi.nlm.nih.gov/pubmed/32646070
http://dx.doi.org/10.3390/ijms21134815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370043/
https://www.ncbi.nlm.nih.gov/pubmed/32646070
http://dx.doi.org/10.3390/ijms21134815

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