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Chemopreventive Agent 3,3′-Diindolylmethane Inhibits MDM2 in Colorectal Cancer Cells

3,3′-Diindolylmethane (DIM) is a naturally derived chemopreventive compound. It comes from glucobrassicin, an indole glucosinolate enriched in cruciferous vegetables, and is formed in the acidic environment of the stomach after ingestion. Mouse double minute 2 homolog (MDM2) is an important, multi-f...

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Detalles Bibliográficos
Autores principales: Gao, Xiang, Liu, Jingwen, Cho, Kwang Bog, Kedika, Samanthreddy, Guo, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370074/
https://www.ncbi.nlm.nih.gov/pubmed/32629830
http://dx.doi.org/10.3390/ijms21134642