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Chemopreventive Agent 3,3′-Diindolylmethane Inhibits MDM2 in Colorectal Cancer Cells

3,3′-Diindolylmethane (DIM) is a naturally derived chemopreventive compound. It comes from glucobrassicin, an indole glucosinolate enriched in cruciferous vegetables, and is formed in the acidic environment of the stomach after ingestion. Mouse double minute 2 homolog (MDM2) is an important, multi-f...

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Detalles Bibliográficos
Autores principales:	Gao, Xiang, Liu, Jingwen, Cho, Kwang Bog, Kedika, Samanthreddy, Guo, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370074/ https://www.ncbi.nlm.nih.gov/pubmed/32629830 http://dx.doi.org/10.3390/ijms21134642

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